Serial serum alkaline phosphatase as an early biomarker for osteopenia of prematurity

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Serial serum alkaline phosphatase as an early biomarker for osteopenia of prematurity

Metabolic bone disease of prematurity is a condition characterized by reduction in bone mineral content (osteopenia). It is a problem faced by very low birth weight (VLBW) infants because of lack of fetal mineralization during the last trimester. Our aim was to assess serum alkaline phosphatase (ALP) level as an early biomarker for osteopenia in premature infants and to estimate an optimal cuto...

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Assessment of Alkaline Phosphatase Activity in Hydatid Cyst Protoscolices and Liver Tissue as a Pathological Biomarker

Introduction: Hydatid cyst disease is caused by the protoscolices of Echinococcus granulosus. Alkaline phosphatase (ALP) enzyme is required for metabolism, physiology, immunology, and nutrients absorption in parasite. The aim of this study was to compare the level of ALP activity (as a pathological biomarker) in hydatid cyst protoscolices (HCP) with that of sheep liver tissue and to determine t...

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Serum Alkaline Phosphatase

phatase may reflect enzyme contributions from bone, liver, and intestine. We have investigated serum alkaline phosphatases in two siblings with hypophosphatasia. After administration of long-chain triglycerides, the major alkaline phosphatase component of their sera was shown to be of intestinal origin on the basis of inhibition by l-phenylalanine. Starch block electrophoresis suggested that th...

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Osteopenia of prematurity.

Bone mineral content of the forearm was measured by photon absorptiometry in 17 preterm infants at a postconceptional age of 40 weeks. Radiographs of the forearm were assessed by Koo's method and plasma alkaline phosphatase activity was also measured at this time. Bone mineral content was significantly but weakly correlated with Koo score and was not significantly correlated with alkaline phosp...

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Alkaline Phosphatase in Serum is a Marker of Human Toxocariasis

Background: The present study was carried out on the human population of Kashmir valley to evaluate the status of the biochemical parameters of infected population. Materials and Methods: Blood samples were collected from 514 individuals, 298 (57.97%) males and 216 (42.02%) females, 187 (36.38%) were found sero-positive for human toxocariasis. Results: Alkaline phosphatase level was found highe...

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ژورنال

عنوان ژورنال: Medicine

سال: 2016

ISSN: 0025-7974

DOI: 10.1097/md.0000000000004837